The nine-month Brexit "phony war" is set to come to an end next week when British Prime Minister Theresa May notifies the European Union of Britain's intention to leave, starting two years of unprecedented negotiations.
May will send a letter to European Council President Donald Tusk on Wednesday to trigger Article 50 of the Lisbon Treaty. Tusk will then send draft negotiating guidelines to the 27 other member states within 48 hours.
That means it will finally be down to business after an at times painstakingly slow drawing of battle lines.
Britain appears to have set its course for a "hard Brexit", where a clean break is favored to regain control over immigration, while the EU's chief negotiator this week spelled out its need for early agreements on citizens' rights, money and borders.
But May has revealed little of her strategy to secure what she calls "the best possible deal" for the world's fifth-largest economy. Her letter next week and Tusk's reply may offer markets keen for details some hints at how rocky the path ahead may be.
"The tone of this process might have implications for sterling markets," said Investec economist Chris Hare.
May has other domestic political issues to tackle as well, including Monday's deadline to form a new regional government in Northern Ireland or risk having its decision-making moved back to London, and a Scottish Parliament vote on Tuesday on whether to second a second independence referendum. On Friday, revised fourth-quarter GDP data will outline how Britain will come to the Brexit negotiating table with a far healthier economy than most predicted last June.
After retail sales suffered their biggest squeeze in nearly 7 years on Thursday as higher inflation begins to bite, timelier indicators next week including mortgage approvals, house prices and consumer confidence may be worth watching more closely.
The potential economic implications of 2016's other major earthquake at the ballot box - the election of U.S. President Donald Trump - could play out at a much faster pace with Friday's do-or-die rescheduled vote on a new healthcare bill.
The vote has been billed by financial markets as a crucial test of Trump's ability to work with Congress to deliver on pro-growth policies like tax cuts and infrastructure spending.
Leaders from Trump's Republican party postponed what was supposed to have been his first legislative victory because of opposition from two flanks in the party on Thursday. Even if it gets approval from the House, the legislation could face an even tougher fight in the Senate, the other chamber of Congress.
A raft of speeches from top Federal Reserve officials - ten days after the bank raised interest rates for the second time in three months - may pale in comparison to the political drama, as could GDP revisions and key manufacturing surveys.
In a date-heavy week around the world, Eurozone flash inflation readings for March stand out after annual price rises surged to a four-year high of 2.0 % in February, zooming up to the European Central Bank's target of "below but close to 2 %".
Rising inflation across the 19-country bloc has put pressure on rate setters to say when and how extraordinary stimulus measures could be scaled back, although still weak underlying figures have limited discussions so far.
"We expect that run to have come to an end this month," wrote economists at RBC Capital Markets, referring to the six consecutive months of year-on-year headline inflation rate rises.
"With the oil price effect abating and underlying inflation still weak, we see headline inflation continuing to moderate from here and falling to 1.5 % year-on-year by year-end."
Next week also brings a string of emerging central bank policy meetings with Czech rate setters set to hold their last meeting before the bank's self-imposed deadline for lifting a 3-1/2-year old currency cap.
Mexico's central bank meets on Thursday after a spike in inflation to an eight-year high prompted its chief to hint at more interest rate hikes following one just last month. Mexican rates are now at their highest in almost eight years.